Transactiva offers a full set of R&D services, starting from the very first idea of a target protein up to a complete, scalable green bioreactor prototype:

 

   Our services include:

– assistance in selecting the best protein candidate and platform

– DNA sequence optimization and expression vector manipulation: Transactiva has developed a unique gene optimization strategy for high expression technology

– plant biomass growth and transformation

– bioreactor cultivation and expansion:

  • Plants regeneration and selection
  • Creation of a homozygous line and a seed banking system
  • Quality System ensuring GACP regime
  • Growth of the bioreactor in soil (greenhouses) or out of soil (hydroponics)
  • Primary processing of rice seeds in the staging area

– setup of an industrially scalable purification strategy: all steps are carefully planned to be scalable and industrially suitable, and exploit already established technologies

– preliminary physico-chemical and functional characterization of target molecule

– preparation of small batches of drug substance (lab scale, not-GMP)

– assistance in planning pre-clinical non regulatory studies  

 Select your platform:

LeafActiva

Nicotiana benthamiana transient expression

 
 
RiceActiva

Oryza sativa stable expression

 

 

Please contact us for a tailored solution to your needs!